Technical CBRN-E Threat Investigator

Title: Technical CBRN-E Threat Investigator Location: Remote-Friendly (Travel-Required) | San Francisco, CA | Washington, DC

About the Role

We are looking for a Technical CBRN-E Threat Investigator to join our Threat Intelligence team. In this role, you will be responsible for detecting, investigating, and disrupting the misuse of Anthropic's AI systems for Chemical, Biological, Radiological, Nuclear, and Explosives (CBRN-E) threats. We are particularly interested in candidates with deep expertise in either chemical defense or biodefense.

You will work at the intersection of AI safety and CBRN security, conducting thorough investigations into potential misuse cases, developing novel detection techniques, and building robust defenses against threat actors who may attempt to leverage our AI technology for developing weapons, synthesizing dangerous compounds, or creating biological harm. Your specialized domain expertise will be critical to protecting against some of the most serious potential misuses of AI systems.

Important context: In this position you may be exposed to explicit content spanning a range of topics, including those of a sexual, violent, or psychologically disturbing nature. This role may require responding to escalations during weekends and holidays.

Responsibilities

• Detect and investigate attempts to misuse Anthropic's AI systems for developing, enhancing, or disseminating CBRN-E weapons, pathogens, toxins, or other threats to harm people, critical infrastructure, or the environment
• Conduct technical investigations using SQL, Python, and other tools to analyze large datasets, trace user behavior patterns, and uncover sophisticated CBRN-E threat actors
• Develop CBRN-E-specific detection capabilities, including abuse signals, tracking strategies, and detection methodologies tailored to dual-use research concerns
• Create actionable intelligence reports on CBRN-E attack vectors, vulnerabilities, and threat actor TTPs leveraging AI systems
• Conduct cross-platform threat analysis grounded in real threat actor behavior, open-source research, and publicly reported programs
• Collaborate with policy and enforcement teams to make informed decisions about user violations and ensure appropriate mitigation actions
• Engage with external stakeholders including government agencies, regulatory bodies, scientific organizations, and biosecurity/chemical security research communities
• Inform safety-by-design strategies by forecasting how threat actors may leverage advances in AI technology for CBRN-E purposes

You may be a good fit if you

• Have deep domain expertise in biosecurity, chemical defense, biological weapons non-proliferation, dual-use research of concern (DURC), synthetic biology, or related CBRN-E threat domains
• Have demonstrated proficiency in SQL and Python for data analysis and threat detection
• Have experience with threat actor profiling and utilizing threat intelligence frameworks
• Have hands-on experience with large language models and understanding of how AI technology could be misused for CBRN-E threats
• Have excellent stakeholder management skills and ability to work with diverse teams including researchers, policy experts, legal teams, and external partners
• Can present analytical work to both technical and non-technical audiences, including government stakeholders and senior leadership

Strong candidates may also have

• Advanced degree (MS or PhD) in biological sciences, chemistry, biodefense, biosecurity, or related field
• Real-world experience countering weapons of mass destruction or other high-risk asymmetric threats
• Experience working with government agencies or in regulated environments dealing with sensitive CBRN-E information
• Background in AI safety, machine learning security, or technology abuse investigation
• Familiarity with synthetic biology, biotechnology, or dual-use research
• Experience building and scaling threat detection systems or abuse monitoring programs
• Active Top Secret security clearance